Literature list by subject:

Drug Discovery

Baell J, Walters MA. Chemistry: Chemical con artists foil drug discovery. Nature. 2014;513(7519):481-3. Epub 2014/09/26.

Begley CG, Ellis LM. Drug development: Raise standards for preclinical cancer research. Nature. 2012;483(7391):531-3.

Dosa PI, Georg GI, Gurvich VJ, Hawkinson JE, Walters MA, Wong HL. From HTS to Phase I: the Institute for Therapeutics Discovery and Development at the University of Minnesota. Comb Chem High Throughput Screen. 2014;17(3):231-40.

Everitt JI. The future of preclinical animal models in pharmaceutical discovery and development: a need to bring in cerebro to the in vivo discussions. Toxicologic pathology. 2015;43(1):70-7.

Lombardino JG, Lowe JA, 3rd. The role of the medicinal chemist in drug discovery--then and now. Nature reviews Drug discovery. 2004;3(10):853-62.

Manns MP. [Role of academic medicine for innovations in development of drugs and biomedicine technology]. Dtsch Med Wochenschr. 2013;138(40):1993-4.

Pelkonen O, Turpeinen M, Raunio H. In vivo-in vitro-in silico pharmacokinetic modelling in drug development: current status and future directions. Clinical pharmacokinetics. 2011;50(8):483-91.

Prinz F, Schlange T, Asadullah K. Believe it or not: how much can we rely on published data on potential drug targets? Nature reviews Drug discovery. 2011;10(9):712.

Pritchard JF, Jurima-Romet M, Reimer ML, Mortimer E, Rolfe B, Cayen MN. Making better drugs: Decision gates in non-clinical drug development. Nature reviews Drug discovery. 2003;2(7):542-53.

Prueksaritanont T, Tang C. ADME of biologics-what have we learned from small molecules? The AAPS journal. 2012;14(3):410-9.

Swinney DC, Anthony J. How were new medicines discovered? Nature reviews Drug discovery. 2011;10(7):507-19.

van de Waterbeemd H, Gifford E. ADMET in silico modelling: towards prediction paradise? Nature reviews Drug discovery. 2003;2(3):192-204.

Wu CY, Benet LZ. Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system. Pharmaceutical research. 2005;22(1):11-23.

Vaudano E. The innovative medicines initiative: a public private partnership model to foster drug discovery. Comput Struct Biotechnol J. 2013;6:e201303017.

Ethics

Scott CT, Borgelt EL, Lee SS. The time is ripe for an ethics of entrepreneurship. Nature biotechnology. 2014;32(4):316-8.

Funding

Ford D, Nelsen B. The view beyond venture capital. Nature biotechnology. 2014;32(1):15-23.

Innovation and Risk Background

Toner M, Tompkins RG. Invention, innovation, entrepreneurship in academic medical centers. Surgery. 2008;143(2):168-71.

Van Dyke M. How much risk are you prepared to take? Nature biotechnology. 2012;30(9):821-4.

Intellectual Property

Kirschenbaum SR. Patenting basic research: myths and realities. Nat Neurosci. 2002;5 Suppl:1025-7.

Lei Z, Juneja R, Wright BD. Patents versus patenting: implications of intellectual property protection for biological research 2009:[36-40 pp.]. Available from:

Murray F, Stern S. Do formal intellectual property rights hinder the free flow of scientific knowledge?: An empirical test of the anti-commons hypothesis. Journal of Economic Behavior & Organization. 2007;63(4):648-87

Reitzig M. Strategic management of intellectual property. MIT Sloan Management Review. 2004;45(3):35-40 

Medical Devices

Rose LM, Everts M, Heller C, Burke C, Hafer N, Steele S. Academic medical product development: an emerging alliance of technology transfer organizations and the CTSA. Clin Transl Sci. 2014;7(6):456-64.

Project Management

Abudi G. The Five Stages of Project Team Development. The.Project.Management.Hut [Internet]. 2010 May 7, 2015:[7pgs p.].

Zappe H. Innovation: Bridging the market gap. Nature. 2013;501(7468):483-5. Epub 2013/09/28. 

Public-Private Partnerships

Capponi L, Trinh-Shevrin C, Cronstein BN, Hochman JS. A public-private partnership: the New York University-Health and Hospitals Corporation Clinical and Translational Science Institute. Clin Transl Sci. 2012;5(3):223-5.

Luijten PR, van Dongen GA, Moonen CT, Storm G, Crommelin DJ. Public-private partnerships in translational medicine: concepts and practical examples. J Control Release. 2012;161(2):416-21.

Murphy DG, Goldman M, Loth E, Spooren W. Public-private partnership: a new engine for translational research in neurosciences. Neuron. 2014;84(3):533-6.

Peng X. University spin-offs: opportunity or challenge? Nat Mater. 2006;5(12):923-5.

Robustness of data

Begley CG. Six red flags for suspect work. Nature. 2013;497(7450):433-4.

Begley CG, Ellis LM. Drug development: Raise standards for preclinical cancer research. Nature. 2012;483(7391):531-3.

Bissell M. Reproducibility: The risks of the replication drive. Nature. 2013;503(7476):333-4.

Everitt JI. The future of preclinical animal models in pharmaceutical discovery and development: a need to bring in cerebro to the in vivo discussions. Toxicologic pathology. 2015;43(1):70-7.

Freedman LP, Inglese J. The increasing urgency for standards in basic biologic research. Cancer research. 2014;74(15):4024-9.

Peers IS, Ceuppens PR, Harbron C. In search of preclinical robustness. Nature reviews Drug discovery. 2012;11(10):733-4.

Prinz F, Schlange T, Asadullah K. Believe it or not: how much can we rely on published data on potential drug targets? Nature reviews Drug discovery. 2011;10(9):712. 

Technology Transfer Background

Aguilar A, Magnien E, Thomas D. Thirty years of European biotechnology programmes: from biomolecular engineering to the bioeconomy. N Biotechnol. 2013;30(5):410-25.

Butler D. Translational research: crossing the valley of death. Nature. 2008;453(7197):840-2. Epub 2008/06/13.

Duda GN, Grainger DW, Frisk ML, Bruckner-Tuderman L, Carr A, Dirnagl U, Einhaupl KM, Gottschalk S, Gruskin E, Huber C, June CH, Mooney DJ, Rietschel ET, Schutte G, Seeger W, Stevens MM, Urban R, Veldman A, Wess G, Volk HD. Changing the mindset in life sciences toward translation: a consensus. Sci Transl Med. 2014;6(264):264cm12. Epub 2014/11/28.

Gehr S, Garner CC. Rescuing the Lost in Translation. Cell. 2016; 165(4): 765-770.

Germann PG, Schuhmacher A, Harrison J, Law R, Haug K, Wong G. How to create innovation by building the translation bridge from basic research into medicinal drugs: an industrial perspective. Hum Genomics. 2013;7:5.

Goldman M. The innovative medicines initiative: a European response to the innovation challenge. Clin Pharmacol Ther. 2012;91(3):418-25.

Klech H, Brooksbank C, Price S, Verpillat P, Buhler FR, Dubois D, Haider N, Johnson C, Linden HH, Payton T, Renn O, See W. European initiative towards quality standards in education and training for discovery, development and use of medicines. Eur J Pharm Sci. 2012;45(5):515-20.

Knowlton AA, Rainwater JA, Chiamvimonvat N, Bonham AC, Robbins JA, Henderson S, Meyers FJ. Training the translational research teams of the future: UC Davis-HHMI Integrating Medicine into Basic Science program. Clin Transl Sci. 2013;6(5):339-46.

Kocher R, Roberts B. The calculus of cures. The New England journal of medicine. 2014;370(16):1473-5.

Ledford H. Biotech boot camp. Nature. 2015;519(7544):402-5.

Paul SM, Mytelka DS, Dunwiddie CT, Persinger CC, Munos BH, Lindborg SR, Schacht AL. How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nature reviews Drug discovery. 2010;9(3):203-14.

Schubert C. Innovation: The big idea of technology transfer. Nature. 2012;484(7393):277-8. Epub 2012/04/17.

Sheft J. Technology transfer and idea commercialization. Nature biotechnology. 2008;26(6):711-2.

Swinney DC, Anthony J. How were new medicines discovered? Nature reviews Drug discovery. 2011;10(7):507-19.

Wright BD, Drivas K, Lei Z, Merrill SA. Technology transfer: Industry-funded academic inventions boost innovation. Nature. 2014;507(7492):297-9. Epub 2014/03/22. 

University and Industry programs

Bouchie A, Allison M, Webb S, DeFrancesco L. Nature Biotechnology's academic spinouts of 2013. Nature biotechnology. 2014;32(3):229-38.

Bouchie A, DeFrancesco L. Nature Biotechnology's academic spinouts of 2014. Nature biotechnology. 2015;33(3):247-55.

Sorkness CA, Pfund C, Asquith P, Drezner MK. Research mentor training: initiatives of the University of Wisconsin Institute for Clinical and Translational Research. Clin Transl Sci. 2013;6(4):256-8.